The United States is experiencing a significant measles resurgence, with Pennsylvania seeing some of the highest case numbers. New data from the Centers for Disease Control and Prevention (CDC) indicate over 4,580 cases nationwide since October 22, doubling 2025’s total. Notably, 96% of those infected in 2026 were either unvaccinated or their vaccination status was unknown, as reported by the CDC.
Pennsylvania’s situation is particularly concerning, with the Department of Health confirming at least 1,338 measles cases across 44 counties this year. The state reported 21 new cases as of October 21. This outbreak has resulted in over 250 hospitalizations and claimed five lives. Lancaster and Mifflin counties are among the areas most affected, largely due to low vaccination rates in local Amish communities. Three of the deceased were Lancaster County residents.
Dr. Debra Bogen, Pennsylvania’s Secretary of Health, held discussions with healthcare providers in Mifflin County to better understand their challenges in addressing the outbreak. Bogen emphasized that state metrics and data alone are not enough; it is crucial to listen to those directly involved in caring for affected communities.
Vaccination remains a key defense against measles. The CDC notes that two doses of the measles, mumps, and rubella (MMR) vaccine provide about 97% protection, while a single dose offers 93% protection. Interest in vaccination is rising, with healthcare providers across Pennsylvania administering over 39,000 measles vaccines in the first three weeks of October, exceeding the usual monthly average of 25,000.
Other states are also grappling with measles outbreaks. New York’s Governor Kathy Hochul declared a disaster emergency due to increasing cases, with over 160 confirmed as of October 20. Utah has reported more than 700 cases this year, although no new diagnoses have occurred in the past three weeks. South Carolina faced its own outbreak earlier in the year, recording at least 997 cases by April, when the outbreak ended.