A compound found in blueberries and grapes shows promise in aiding muscle cells to break down stored fat, according to research conducted in Japan. The compound, known as pterostilbene, was observed to reduce fat accumulation in cultured mouse muscle cells during laboratory experiments.
Understanding Pterostilbene
Pterostilbene is an antioxidant present in blueberries, grapes, and various berries. Previously linked to metabolic advantages, its effects on skeletal muscle were not well explored. Recent findings published in the journal Food Bioscience on September 1st indicate that pterostilbene diminishes abnormal fat buildup by encouraging cells to break down stored fat. Factors like high-fat diets, inactivity, and aging can lead to fat accumulation.
Too much fat within muscle cells can impact the body’s use of glucose and fatty acids and might contribute to insulin resistance.
Research Insights
Takakazu Mitani, an associate professor at Shinshu University, emphasized that these results form a basis for creating foods and supplements focused on muscle fat metabolism. The team identified pterostilbene’s ability to decrease fat accumulation while preserving a protein, PPAR-delta, which regulates fat processing in cells.
Additional research is needed to identify other natural compounds that help protect PPAR-delta.
Complexity in Human Metabolism
Johannah Katz, a registered dietitian, noted that future studies in humans and animals are essential to ascertain if these effects extend beyond laboratory conditions. Human metabolism involves digesting, absorbing, and metabolizing compounds, making it complex.
The Role of Blueberries and Grapes
While the study offers insights into reduced fat accumulation mechanisms, it differs from claiming that consuming blueberries or pterostilbene supplements directly triggers fat loss. Katz stressed that despite the results in mouse studies, eating blueberries doesn’t guarantee fat loss. Blueberries and grapes remain nutritious options for various health benefits, but this study alone doesn’t establish direct fat reduction in humans.
Further exploration and direct comments from study authors could provide additional clarity.